ABSTRACT
Background: Random blood sugar (RBS) is a commonly performed screening test for type 2 diabetes in both programmatic as well as clinical settings. Previous calorie intake is known to affect the results of RBS. So, present study was conducted to assess the effect of previous calorie intake on sensitivity, specificity, positive and negative predictive values (NPV) and accuracy of RBS.Methods: A cross sectional study was done in 317 patients of 30 years or more using systematic random sampling in a general outpatient department of a district hospital. All the patients underwent RBS measurement. History of calorie intake in past 1-2 hours before undergoing RBS was taken. Screening test parameters of RBS was evaluated using oral glucose tolerance test as clinical reference.Results: This study found that calorie consumption of 200 kcal or more significantly affected the screening test result of RBS. When patient had consumed 200 kcal or more in last 1-2 hours, the sensitivity of RBS is 90.0%, specificity is 57.4%, positive predictive value (PPV) is 26.9% and NPV is 97.1%. Whereas, these parameters are 63.3%. 78.5%, 43.6% and 88.9% respectively when patient had consumed less than 200 kcal in last 1-2 hours before RBS.Conclusions: Sensitivity and NPV of RBS is higher if patient had consumed more than 200 kcal 1-2 hours prior to RBS whereas specificity and PPV is higher if patient had consumed less than 200 kcal. Taking history of quantity and time of last meal would be helpful to better interpret the screening test results of RBS.
ABSTRACT
Background: Morphometric analysis of the foramen magnum of dry human skulls in Gujarat region was carriedout to demonstrate the anatomical variations in morphology. The measurements of the foramen magnum areclinically important because vital structures passing through it. There are certain diseases associated withcompression of structure present in foramen magnum like arnold chiari malformation (tonsillar herniation),achondroplasia, stenosis of foramen magnum, meningioma and atlanto-occipital fusion.Objectives: The aim of this study was to measure anteroposterior & transverse diameter of foramen magnum,surface area and index of foramen magnum and to observe its various shapes.Materials and methods: 326 dry skulls of adult human being were studied. Antero-posterior and TransverseDiameter were measured by using a digital vernier caliper. The surface area and foramen magnum index werecalculated. The cranial base was visually assessed for the shape of foramen magnum.Results: The mean antero-posterior and transverse diameter of the foramen magnum were 34.18 ± 2.74 mm and28.49 ± 2.13 mm respectively. The mean surface area and the foramen magnum index were 766.86 ± 104.76 mm2and 83.60 ± 6.21 mm respectively. The percentages of different shapes of foramen magnum were: Oval (42.33%),Round (32.82%), Tetragonal (8.59%), Hexagonal (7.67%), Pentagonal (4.60%), and irregular (3.99%).Conclusion: The knowledge of various dimensions & shape of the foramen magnum help to determine somemalformations like arnold chiari syndrome in which the transverse diameter is increased. The antero-posteriordiameter of foramen magnum was more than the transverse diameter and most common shape of foramenmagnum was found to be Oval.